Sildenafil price comparison

WHAT IS VIAGRA CONNECT®?

Viagra Connect® is a treatment for Erectile Dysfunction (ED) containing 50mg of sildenafil. It is available to patients over 18 years with ED directly from pharmacy without a doctor’s prescription.

To save you time when visiting your local Hickey’s Pharmacy, complete the form (see link below).

Viagra Connect® as a treatment for Erectile Dysfunction

Erectile dysfunction (ED) is the inability to achieve or maintain an erection sufficient to have sex.

Erection problems can put a strain on relationships. They can also be a warning sign of a health condition or disease you might not be aware of. That’s why it’s important to take action and find a solution for your ED.

IS VIAGRA RIGHT FOR YOU?

Daily life can sometimes get in the way of your sex life. When it does, Viagra Connect is here to help.

Who it’s for: Viagra Connect is for adult men (over 18 years of age) who have erection problems (EPs) – what doctors might call erectile dysfunction (ED).

Who it isn’t for: If you are a woman, a man under 18, or do not have EPs, then Viagra Connect isn’t the right treatment for you.

Where you buy it: From our trusted partner ChemistDirect, from other online pharmacies, and from your local pharmacy. No prescription needed.

Are you taking other medicines? Some medicines can interact with Viagra Connect, so you’ll be asked what else you might be taking before you can buy it.

Do you have any other health conditions? Some men will have issues with their health that make Viagra Connect unsuitable for them. This is why you’ll be asked a few straightforward questions about your health before you can buy it.

Try and do the following to get the most out of Viagra Connect:

  • Get in the mood. Viagra Connect usually starts to work within 30–60 minutes, so you can be ready when you need to be. Remember, taking Viagra Connect isn’t going to give you an instant erection; you need to be sexually aroused for it to work. You and your partner should engage in foreplay, just like you would if you weren’t taking medicine for erectile dysfunction (ED) – the medical name for erection problems (EPs)
  • Relax. There’s no rush. Viagra Connect works for up to 4 hours after you take it – it will still work within this period of time, in response to sexual stimulationWatch what you eat. Viagra Connect can be taken with or without food. But if you take it after a meal that has a lot of fat in it, like a burger and chips, it might take a bit longer to start working
  • Get familiar. If it’s been a long time since you had an erection, try masturbating before having sex so you can get used to the feeling of having an erection again
  • Don’t give up. If Viagra Connect doesn’t work first time, don’t worry, getting used to having an erection again can take a while. Next time you’re ready, take another tablet – but never more than 1 a day
  • Keep your options open. If Viagra Connect doesn’t work for you after several separate tries, talk to your pharmacist or doctor. You might need a different treatment – either for your erection problems or for a condition that is contributing to them
  • Always read the instructions. The Patient Information Leaflet, which you’ll find in the Viagra Connect box, tells you exactly what to do to get the best results from Viagra Connect, so it’s worth reading. In fact, it’s essential
ceivable that I could get this argument convincingly passed?

HOW DOES VIAGRA CONNECT® WORK?

Theby Viagra Connect® (sildenafil citrate 100mg) helpstreat erectile dysfunction– theedu{�erectile dysfunction – by stopping the flow of nitric oxide!

Viagra Connect works by allowing the blood vessels in your penis to relax. This increases blood flow into your penis, thiss...

Viagra 50mg tablet contains an active component such as Sildenafil. This medication is used to treat erectile dysfunction (ED) in men. It contains the active ingredient sildenafil citrate, which belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. It increases blood flow to the penis during sexual stimulation, which helps men achieve and maintain an erection. Viagra may have side effects, including headache, flushing, dizziness, upset stomach, nasal congestion, and vision changes. It should not be taken with certain medications or conditions, so it's crucial to consult a healthcare professional before using it. Erectile dysfunction can have a profound impact on a man's self-esteem and quality of life. By addressing ED, this medication can help improve a person's sense of well-being and overall happiness.

Individuals with a history of cardiovascular diseases, such as heart problems (angina, heart failure, irregular heartbeats) or recent heart attack, should exercise caution when using Viagra. The sexual activity itself can strain the heart and can further increase the strain by increasing blood flow. Consult with a healthcare professional to assess the risks and benefits in such cases. This medication can cause a mild decrease in blood pressure. Caution is advised for individuals with low blood pressure or those taking medications that lower blood pressure, as combining these can lead to potentially harmful interactions. People with severe liver or kidney disease may experience slower elimination of Viagra from the body, leading to a prolonged effect. Dosage adjustments may be necessary in such cases.

What is Erectile dysfunction?
  • A man experiences the first signs of erectile dysfunction (ED), such as irritation at first application and difficulties getting an erection until fairly soon.
  • The severity and duration of erectile dysfunction can be influenced by various factors, including age, weight, general health, BMI, other health conditions, and the specific condition being treated.
  • The cause can begin either cause or unrelated to medication related. Therefore, it's crucial to consult a healthcare professional before taking medication to assess underlying causes.

When using Viagra, it is important to exercise caution. Consult with a healthcare professional if you're considering taking this medication to treat your erectile dysfunction. They can help you determine the appropriate dose for your specific needs and manage any potential issues.

Viagra 50mg tablet can be taken with or without food. It is recommended to take it at approximately the same time of day. However, it is recommended to take the dose on an as-needed basis.

Abstract

The purpose of this study was to determine whether the concentration of sildenafil in human plasma could be affected by changes in the pH of the medium. Human plasma was prepared by the method of microfiltration and characterized by electrophoretic mobility, binding to phosphodiesterase-5, and binding to the Sildenafil hydrochloride salt. The influence of the pH of the plasma on the binding of sildenafil to phosphodiesterase-5 was determined by measuring the specific binding of the drug to the Sildenafil hydrochloride salt in human urine. The effect of the concentration of the plasma on the binding of the drug to phosphodiesterase-5 was also determined. After the treatment with increasing concentrations of sildenafil, the concentration of the drug in plasma increased from 9.7 to 13.1 mg/ml. In addition, the effect of the concentration of the plasma on the binding of the drug to phosphodiesterase-5 was also determined. The results of this study suggest that a higher concentration of sildenafil can be more effective in the treatment of erectile dysfunction in the presence of sexual stimulation.

Keywords:Sildenafil, phosphodiesterase-5, Sildenafil hydrochloride, phosphodiesterase-5, plasma, ED, sildenafil hydrochloride, phosphodiesterase-5

Introduction

Sildenafil, a popular medication used for erectile dysfunction, is a well-known inhibitor of phosphodiesterase-5 (PDE-5). The primary mechanism of PDE-5 action involves the inhibition of the PDE-5 enzyme, which is responsible for the degradation of cyclic guanosine monophosphate (cGMP). Inhibition of PDE-5 has been shown to have a significant effect on erectile function in many studies.

In recent years, the use of sildenafil has gained considerable attention as an effective treatment for erectile dysfunction. In order to investigate the influence of the concentration of sildenafil on the effects of PDE-5 inhibition, we have prepared a blood plasma preparation of sildenafil, as well as the corresponding blood plasma samples for the determination of PDE-5 in the plasma of healthy male volunteers. Blood samples were obtained from healthy volunteers in order to determine the effects of the concentration of sildenafil on the concentration of PDE-5 in the plasma of patients with erectile dysfunction.

PDE-5 is an enzyme found in the plasma of various types of tissues and has been shown to be present in the tissues of all the different tissues of the human body. In the blood plasma, the concentration of PDE-5 is found to be lower in males than in females. The plasma concentrations of PDE-5 are inversely proportional to age and the plasma concentrations of PDE-5 are also inversely proportional to age and the plasma concentrations of PDE-5 are also inversely proportional to age. It has been shown that plasma levels of PDE-5 are lower in men and females.

The plasma concentration of sildenafil in healthy subjects was determined by spectrophotometric methods. The blood plasma samples were prepared from healthy volunteers by conventional methods. The plasma samples were then analyzed for the presence of PDE-5 by measuring the plasma levels of sildenafil.

In order to determine the effect of the concentration of sildenafil on the blood plasma concentrations of PDE-5 in the plasma of healthy males, we prepared the blood plasma samples of men and women. We measured the plasma levels of sildenafil using high-performance liquid chromatography (HPLC) method. The blood samples were analyzed for the presence of sildenafil and its metabolites. The concentrations of sildenafil in the plasma of healthy males and men were also determined using high-performance liquid chromatography.

The effect of the concentration of sildenafil on the blood plasma concentrations of PDE-5 in healthy males was determined by the method of pharmacokinetics. The pharmacokinetics of sildenafil in healthy males and healthy males were investigated by using a non-compartmental pharmacokinetic model. The pharmacokinetics of sildenafil in healthy males and healthy males were assessed by the method of pharmacokinetics. The effect of the concentration of the plasma concentration of sildenafil on the pharmacokinetics of sildenafil was also determined.

Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.

Dosage and Administration

Sildenafil is available in 25mg, 50mg, and 100mg strengths.

  • The usual starting dose is 50mg, taken approximately one hour before sexual activity.
  • Dosage can be adjusted depending on individual response and tolerability.
  • Take only one tablet in 24 hours, with or without food.
  • Avoid grapefruit juice, as it can increase the risk of side effects.
  • A high-fat meal may delay onset of action.

Effectiveness

Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.

Side Effects

Common side effects include:

  • Headache
  • Flushing
  • Nasal congestion
  • Indigestion

Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.

Contraindications

Sildenafil should not be used by those:

  • Taking nitrates for chest pain
  • With severe heart or liver conditions
  • Under 18 years of age
  • With certain medication interactions (e.g. alpha-blockers, antifungals, antibiotics)

Interactions

Inform your doctor of all medications and supplements before use. Interactions may occur with:

  • Nitrates
  • Alpha-blockers
  • Some antibiotics and antifungal medicines

Alcohol and Heart Conditions

Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.

Availability and Cost

Sildenafil is available by prescription only in the UK.

  • Generic versions are more affordable than branded Viagra.
  • Supplied by licensed UK pharmacies such as Online Chemist.
  • Avoid counterfeit products from unregulated websites.

Take Control of Your Sex Life

Don’t let ED affect your confidence or relationships. Buy Sildenafil tablets online today and experience more satisfying erections — securely, discreetly, and from our trusted UK-regulated pharmacy.

✅ Free online consultation✅ Fast UK delivery✅ Discreet packaging✅ GPhC-regulated

now and get back to enjoying intimacy with confidence.

Store Notice: Orders placed after 11:00 AM on Friday, 23 May 2025 will be processed on the next working day, Tuesday, 27 May 2025, due to the bank holiday weekend. Thank you for your understanding.

https://www.gov.uk/patentsystem/usg.asp?province=gov.